Research Officer, Chemical Biology (GIS)
Salary undisclosed
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The Yu Lab (launching in April 2025) at the Genome Institute of Singapore (GIS), A*STAR, is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA- and DNA-targeted drug discovery. Our goal is to re-engineer small molecules and antisense oligonucleotides (ASOs) for gene-selective regulation, paving the way for rational drug design. By leveraging cutting-edge gene-targeting strategies, structural biology, sequencing technologies, and computational approaches, we aim to unlock RNA and DNA as precise therapeutic targets, addressing diseases linked to genomic dysregulation and undruggable pathways.
Why Join Us?
The Genome Institute of Singapore (GIS), A*STAR is the national flagship program for genomic sciences in Singapore, with a mission to use genomics to improve public health and drive biomedical innovation. GIS offers a highly competitive remuneration package and relocation assistance. Singapore is a vibrant, cosmopolitan city-state at the heart of Asia, known for its excellent quality of life, world-class research infrastructure, and strong government support for scientific innovation.
We are looking for a highly motivated Research Officer to join our team and contribute to innovative RNA- and DNA-targeted therapeutic discovery.
Research Officer (2-year contract, renewable)
Responsibilities:
Develop and optimize cellular assays to evaluate the efficacy of RNA-targeting strategies in cells.
Assist in designing and conducting experiments related to CRISPR, small-molecule screening, and ASO development.
Perform molecular biology experiments, including CRISPR-based gene regulation, plasmid construction, stable cell line establishment, and RNA-seq library preparation.
Maintain lab operations, including reagent preparation, consumable ordering, budget tracking, and equipment maintenance.
Engage in literature reviews, research discussions, and collaborative projects.
Ensure project milestones are met and contribute to manuscript preparation.
Requirements:
Degree in Biological Sciences, Chemical Biology, or related fields.
Experience in molecular biology, cell culture, RNA biology, CRISPR, or sequencing technologies.
Strong organizational skills and a positive, eager-to-learn attitude.
Ability to work both independently and collaboratively in a fast-paced research environment.
Application Details
For inquiries or to apply, please email your CV and brief research interest to Zutao Yu ([email protected]; [email protected]). More information about the lab can be found online: www.yucleiclab.com and https://www.researchgate.net/profile/Yu-Zutao.
Join us in advancing RNA and DNA-targeted therapeutics and making an impact in functional genomic medicine!
The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.
Type of Employment : Full-Time
Work Location : Biopolis
Why Join Us?
The Genome Institute of Singapore (GIS), A*STAR is the national flagship program for genomic sciences in Singapore, with a mission to use genomics to improve public health and drive biomedical innovation. GIS offers a highly competitive remuneration package and relocation assistance. Singapore is a vibrant, cosmopolitan city-state at the heart of Asia, known for its excellent quality of life, world-class research infrastructure, and strong government support for scientific innovation.
We are looking for a highly motivated Research Officer to join our team and contribute to innovative RNA- and DNA-targeted therapeutic discovery.
Research Officer (2-year contract, renewable)
Responsibilities:
Develop and optimize cellular assays to evaluate the efficacy of RNA-targeting strategies in cells.
Assist in designing and conducting experiments related to CRISPR, small-molecule screening, and ASO development.
Perform molecular biology experiments, including CRISPR-based gene regulation, plasmid construction, stable cell line establishment, and RNA-seq library preparation.
Maintain lab operations, including reagent preparation, consumable ordering, budget tracking, and equipment maintenance.
Engage in literature reviews, research discussions, and collaborative projects.
Ensure project milestones are met and contribute to manuscript preparation.
Requirements:
Degree in Biological Sciences, Chemical Biology, or related fields.
Experience in molecular biology, cell culture, RNA biology, CRISPR, or sequencing technologies.
Strong organizational skills and a positive, eager-to-learn attitude.
Ability to work both independently and collaboratively in a fast-paced research environment.
Application Details
For inquiries or to apply, please email your CV and brief research interest to Zutao Yu ([email protected]; [email protected]). More information about the lab can be found online: www.yucleiclab.com and https://www.researchgate.net/profile/Yu-Zutao.
Join us in advancing RNA and DNA-targeted therapeutics and making an impact in functional genomic medicine!
The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.
Type of Employment : Full-Time
Work Location : Biopolis