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Research Fellow (Condensate-Membrane Interactions in Health and Disease)

Salary undisclosed
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Institute For Digital Molecular Analytics & Science (IDMxS) is a unique interdisciplinary Research Centre of Excellence (RCE), funded by National Research Foundation, Ministry of Education (Singapore), Nanyang Technological University and National University of Singapore. Hosted by NTU, IDMxS is focused on development of core science to drive a paradigm shift in molecular detection and analysis to link the biomolecular world of life with the networked world of technology.

The Organelle Dynamics and Function Lab at IDMxS/SBS-NTU (www.bussilab.com) seeks a Research Fellow to study organelle-biomolecular condensate interactions using advanced light microscopy and iPSC disease models. PhD in cell biology or related field required. As part of our team, the candidate will use biophysics methods and super-resolution microscopy to explore how biomolecular condensates regulate organelle and cellular function. For more details about the lab, please view, www.bussilab.com

Key Responsibilities
  • Conduct cutting-edge research using high-resolution light microscopy to study membrane, condensate, and organelle dynamics.
  • Investigate organelle dysfunction using iPSC models of disease.
  • Collaborate with a multidisciplinary team to advance the field of organelle basis of disease mechanisms.
  • Record, manage, and store collected data in line with NTUs data management policies
  • Disseminate results in the form of peer-reviewed publications and presentations at international conferences
  • Contribute to a major, multi-year research project funded by a competitive national grant (NAP, 1.5M).
  • Utilize shared laboratory resources and contribute to efficient use of grant funds. Primary user of a state-of-the-art super-resolution microscope valued at over $1M
  • Extensive use of shared core facilities including confocal and super-resolution microscopes, and flow cytometry instruments.
  • Responsible for managing and analyzing large datasets generated from high-resolution imaging and -omics experiments (estimated at 10-20TB/year).

Job Requirements
  • PhD in cell biology, biochemistry, or related fields, with a focus on membrane trafficking or biophysics.
  • Experience in confocal and/or super-resolution microscopy and image analysis. Experience with protein purification, iPSCs, and/or biophysics methods is preferred.
  • Strong written and verbal communication skills in English.
  • Demonstrable experience as peer-reviewed publications is preferred.
  • Motivation and leadership in pursuing challenging scientific questions.
  • Be able to work independently and collaborate efficiently in a highly diverse and interdisciplinary team.

We regret that only shortlisted candidates will be notified.

Hiring Institution: NTU